Establishment of New Final Handling

Competencies

Steering group
Project management
Project/design engineer
Specialist competencies
Drawing resources

Project phases

Feasibility study
Conceptual design
Basic design
Detailed design
Installation
Commissioning & handover
Contact me for more information
Kjeld Lemke
Director, Pharma Section
Phone: +45 2679 5755

Project description

To expand the capacity of Syntese A/S’ API handling a new facility is established that contains the three final steps in the production of Mesalazin bulk. The facility includes a centrifuge, a vacuum dryer and powder management, including supply plants (GMP and non-GMP). In addition, the facility is prepared for installation of an extra process line for API handling as well as two pieces of trap tanks.

The process

Syntese has managed the overall project management with regard to the establishment of the building, procurement of a centrifuge, a vacuum dryer, ventilation, utility water installations, heating and electric and SRO installations.

Process Engineering has reported to the project manager from Syntese and provided consulting services on supply plants (GMP and non-GMP) and powder management.

The supply plants included steam, condensate, refrigeration, vacuum, water, waste water, alcohol, process water, air pressure and nitrogen. To streamline the process we focused on using commissioning tests as raw data during the qualification. All of this took place in partnership with Syntese.

Projektledelse

Service and scope of the project

Our service and the scope of the project include:

  • PI Diagram
  • Inventories
  • Tender material and requirements specification
  • Installation tender
  • Installation and construction management
  • Start-up management
  • Start-up engineer(s)
  • SAT and supervision
  • Documentation